Mental Health and Methylation

     According to William W. Walsh, approximately 70% of the population has normal methylation, 22% are undermethylated, and 8% are hypermethylated. However, more than two-thirds of people diagnosed with a behavioral or mental disorder exhibit a methylation imbalance.

    Diseases and signs associated with methylation imbalances:

Undermethylation: OCD (obsessive compulsive disorder), autism, seasonal allergies, high homocysteine, low pain tolerance, addictive tendencies.

Overmethylation: Anxiety and panic attacks, schizophrenia, attention deficit hyperactivity disorder, sleep disturbance, food and chemical sensitivities; estrogen intolerance, antihistamine intolerance; adverse reaction to selective serotonin reuptake inhibitor antidepressants.

    Most people diagnosed with mental disorders exhibit severely imbalanced methylation. Accurate diagnosis of methylation status through genetic testing is essential for effective treatment. A person’s methylation status is established during the first months of development in the womb and this condition tends to persist throughout life.

Reference:

Walsh, William J. Nutrient Power. New York: Skyhorse Publishing, 2014.

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