Glutathione and oxidative stress

    Glutathione metabolic activities include Phase II conjugation reactions, prostaglandin synthesis and reduction/ oxidation reactions. Any condition that increases oxidative stress tends to increase the demand for hepatic glutathione production.

 

Organ pathology associated with decreased glutathione status

Hepatic

Cardiovascular

 Lungs

Kidney

Genitourinary

Endocrine Gastrointestinal

Gallbladder

Musculoskeletal

Neurological

 

Specific conditions associated with reduced glutathione status

Schizophrenia

Autism

Cataracts

Accelerated aging

Hyperlipidemia

Hepatitis

AIDS

Adult respiratory distress syndrome

Cystic fibrosis

Diabetes

Environmental toxicity