Pyroluria questionnaire

Equivalent value

0= rarely/never; 1= occasionally/once every two weeks; 2= sometimes/once or twice a week; 3= often/a few times a week; 4= always/daily

Please review the list below and mark the most appropriate answer. If you marked more than 6 questions in severity scores 2, 3 and 4, it is recommended to confirm pyroluria with the hydroxyhemopyrroline-2-one (HPL) test.

Little or no memory of dreams 0 1 2 3 4

White spots on fingernails 0 1 2 3 4

Poor morning appetite +/- tendency to skip breakfast 0 1 2 3 4

Morning sickness 0 1 2 3 4

Pale skin +/- slightly tanned +/- burns easily in the sun 0 1 2 3 4

Sensitivity to bright light 0 1 2 3 4

Hypersensitivity to noise 0 1 2 3 4

Reading difficulties (e.g., dyslexia) 0 1 2 3 4

Poor ability to cope with stress 0 1 2 3 4

Mood swings or temper outbursts 0 1 2 3 4

Histrionic (dramatic) tendencies 0 1 2 3 4

Argumentative/liking for arguments 0 1 2 3 4

New situations or changes in routine (i.e. travel) that are particularly stressful 0 1 2 3 4

Much greater alertness and capacity in the evening compared to the morning 0 1 2 3 4

Poor short-term memory 0 1 2 3 4

Abnormal distribution of body fat 0 1 2 3 4

Belonging to an all-girl family with similar sisters 0 1 2 3 4

Dry skin 0 1 2 3 4

Anxiety 0 1 2 3 4

Reaching puberty later than normal 0 1 2 3 4

Difficulty digesting, dislike of protein, or history of vegetarianism 0 1 2 3 4

Tendency to be a loner and/or avoid large groups of people 0 1 2 3 4

Stretch marks on the skin 0 1 2 3 4

Poor sense of smell or taste 0 1 2 3 4

Feels very uncomfortable around strangers 0 1 2 3 4

Often feels fatigued 0 1 2 3 4

Tendency to overreact to tranquilizers, barbiturates, alcohol, or other drugs (in other words, a little produces a powerful response) 0 1 2 3 4

A tendency to anemia 0 1 2 3 4

A family history of mental illness or alcoholism 0 1 2 3 4

Easily upset by criticism 0 1 2 3 4

Sweet (fruity) smell when breathing or sweating when ill or stressed 0 1 2 3 4

Prone to acne, eczema, or psoriasis 0 1 2 3 4

A tendency to feel anxious, fearful, and carry inner tension throughout life 0 1 2 3 4

Difficulty remembering past events or people 0 1 2 3 4

Bouts of depression or nervous exhaustion 0 1 2 3 4

Prone to frequent colds or infections 0 1 2 4