The impact of the ketogenic diet on neurological diseases

    The ketogenic diet promotes neuroprotection through:

• Reduction of oxidative stress and inflammation.

• Improvement of mitochondrial function.

• Regulation of neurotransmitters (e.g., GABA and glutamate).

• Activation of molecular pathways such as Nrf2 and PPARγ.

𝗘𝗳𝗳𝗲𝗰𝘁𝘀 𝗼𝗻 𝗦𝗽𝗲𝗰𝗶𝗳𝗶𝗰 𝗖𝗼𝗻𝗱𝗶𝘁𝗶𝗼𝗻𝘀:

• 𝗘𝗽𝗶𝗹𝗲𝗽𝘀𝘆: Decreases seizure frequency by stabilizing neuronal excitability and enhancing mitochondrial energy production.

• 𝗔𝗹𝘇𝗵𝗲𝗶𝗺𝗲𝗿’𝘀: Reduces β-amyloid and tau accumulation, improves brain metabolism, and decreases inflammation.

• 𝗣𝗮𝗿𝗸𝗶𝗻𝘀𝗼𝗻’𝘀: Reduces oxidative stress, enhances motor function, and decreases inflammatory microglial activity.

• 𝗠𝘂𝗹𝘁𝗶𝗽𝗹𝗲 𝗦𝗰𝗹𝗲𝗿𝗼𝘀𝗶𝘀: Reduces demyelination and improves immune function, with anti-inflammatory effects.

• 𝗛𝘂𝗻𝘁𝗶𝗻𝗴𝘁𝗼𝗻’𝘀: Shows promising neuroprotective effects, neurotransmitter regulation, and improved mitochondrial function.

    The ketogenic diet appears to be a promising complementary therapeutic strategy for various neurological disorders, though further research is required to fully understand its mechanisms.

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