The Role of Lifestyle in Autoimmune Disease

Lifestyle choices have a profound influence on your health, often more significant than you might think. When it comes to autoimmune disease, this influence becomes even more evident. From toxin exposure and stress management to sleep patterns and exercise routines, your lifestyle habits can either stoke or quell the inflammatory fires within you, ultimately shaping the course and management of your autoimmune disease.

Exposure to toxins

 Both exposure to environmental toxins (such as air pollution, heavy metals, food additives, plastics, pesticides, and recreational drugs) and toxins produced by the bacteria in your gut can trigger your immune system and cause inflammation.

Buying organic and unprocessed foods as much as possible, drinking filtered tap water, and purchasing only natural household cleaners and personal care products are some of the first steps you can take to reduce your exposure.

Additionally, try to minimize your exposure to heavy metals. The metals to watch out for include mercury, lead, cadmium, and aluminum.

The two main sources of mercury exposure are seafood and dental amalgams. If you already have mercury fillings, you’ll want to have them removed.

Lead is another important heavy metal found in contaminated water, lead paint, gasoline, batteries, and more. Older homes are especially known to be contaminated with lead.

The last two common heavy metals are cadmium (cigarettes are the main likely source of exposure) and aluminum. Aluminum can be found in many personal care products, such as deodorants, as well as in our drinking water and cookware. It’s best to use stainless steel, glass, or ceramic cookware.

Beware of plastics, which are a common source of known toxic chemicals, such as BPA, phthalates, and diethylstilbestrol, among others. Reduce your use of plastics whenever possible. Do not heat food in plastic containers in the microwave, and avoid using plastic wrap to cover food for storage or heating in the microwave. Use glass or ceramic containers whenever possible to store food, and do not refill plastic water bottles, especially if they have been left in the sun. It is also important to ensure that your living and working spaces are free of mold. While there is not enough evidence that mold exposure directly causes autoimmune diseases, it may play a role in worsening existing health problems, especially in people with weakened immune systems. There is some connection between mold exposure and worsening conditions such as inflammatory bowel disease or autoimmune diseases, but no causality has yet been demonstrated. More research is needed, but the evidence we have now suggests that mold and its toxins can disrupt the immune system and potentially lead to autoimmune problems down the road. One last thing you can do to mitigate your exposure to toxins is to fast. That’s right! As you consume food throughout the day, your digestive system, liver, and kidneys are constantly working to absorb nutrients and eliminate toxins. Intermittent fasting, where you take an extended break from eating, allows your body to rest and break down food waste more effectively, leading to more effective detoxification and reduced gut inflammation. Additionally, fasting can help increase the production and activity of certain enzymes involved in detoxification, as well as optimize cellular repair. In fact, one study shows that prolonged fasting for 3 days or more (drinking only water and eating less than 200 calories per day) can “reset” components of your immune system, shifting stem cells from a dormant state to a self-renewing state. While the research is promising, more research is needed in this area.

 Exercise

Did you know that when you are physically inactive, you are not only missing out on the physical and psychological benefits of exercise, but you are also potentially exacerbating your autoimmune condition?

In fact, exercise helps to bolster your body’s defense mechanisms in several ways. One of its notable effects is the release of anti-inflammatory compounds.

When you get off the couch and exercise, your body increases its production of anti-inflammatory cytokines. These small proteins act as peacemakers in your immune system, helping to balance the pro-inflammatory responses that, when overactive, can contribute to autoimmune diseases. By promoting this delicate balance, exercise prevents chronic inflammation from getting out of control, reducing the risk of autoimmune flare-ups.

Additionally, exercise improves circulation, acting as a turbocharger for your cardiovascular system. As you sweat, your heart pumps blood more efficiently, increasing the flow of oxygen-rich blood to your body’s tissues. This oxygenation is vital to the health of your cells, including your immune cells, ensuring they have the energy they need to perform their immune-boosting functions.

At the same time, exercise facilitates the delivery of essential nutrients to your tissues, allowing your immune system to operate at peak efficiency.

In addition, improved circulation assists in the removal of cellular debris and metabolic waste products, promoting tissue health and reducing the risk of chronic inflammation. By making exercise a part of your routine and aiming for at least 40 minutes of moderate-intensity activity four times per week, you are giving your immune system the tools it needs to remain resilient and ready to protect your body from autoimmune threats.

 Sleep

Quality sleep and its impact on autoimmune disease should not be underestimated. During these crucial nighttime hours, your body repairs damaged tissue, regulates hormones, and strengthens your immune system.23 When you don’t get enough sleep, you’re essentially calling off your body’s maintenance crew prematurely, leaving multiple systems in jeopardy.

 One significant way sleep affects autoimmune disease is through regulating inflammation. Lack of sleep can throw your body’s inflammatory response out of whack, leading to chronic low-grade inflammation. This constant state of inflammation can exacerbate autoimmune conditions, as your immune system becomes more reactive and prone to attacking healthy cells and tissues.

In addition, inadequate sleep can disrupt the balance of hormones that govern immune function, making your immune system less effective at distinguishing between threats and normal bodily functions. To support your immune system and manage autoimmune disease, prioritize getting the recommended 7 to 9 hours of quality sleep each night.

 Avoid alcohol and stimulants such as caffeine and nicotine, as they can negatively impact nervous system function, contributing to daytime fatigue and disrupting normal sleep patterns.

 Stress

Is it possible that your mental and emotional well-being may have contributed to the development of your autoimmune disease(s)?

Surprisingly, studies have found a higher incidence of autoimmune diseases among those who have previously struggled with stress-related disorders. In fact, up to 80% of patients reported experiencing unusual emotional stress prior to the onset of their autoimmune conditions!

In one revealing study, researchers examined a massive cohort of over 100,000 people diagnosed with stress-related disorders. They then compared their likelihood of developing an autoimmune disease at least one year later with that of 126,000 of their own siblings and another million individuals who had not experienced such stress-related disorders. The findings were striking—those diagnosed with stress-related disorders were not only more likely to develop autoimmune diseases, but they were also more likely to suffer from multiple autoimmune conditions, especially if they were younger.

The exact mechanics behind the dance between psychological stress and autoimmune physiology are still shrouded in mystery. But here’s what we do know: Stress has a knack for increasing inflammation, increasing inflammatory cytokines and triggering neuroendocrine hormones, which can also amplify cytokine production.

            Stress can also have an indirect effect, impacting many aspects of your health, from the way you sleep and your food choices to your alcohol or drug consumption and exercise habits. Autoimmune diseases, once they take hold, can generate significant stress, creating a challenging cycle. 

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